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A novel role for the actin-binding protein drebrin in regulating opiate addiction
Persistent transcriptional and morphological events in the nucleus accumbens (NAc) and other brain reward regions contribute to the long-lasting behavioral adaptations that characterize drug addiction. Opiate exposure reduces the density of dendritic spines on medium spiny neurons of the NAc; howeve...
Autores principales: | Martin, Jennifer A., Werner, Craig T., Mitra, Swarup, Zhong, Ping, Wang, Zi-Jun, Gobira, Pedro H., Stewart, Andrew. F., Zhang, Jay, Erias, Kyra, Siemian, Justin N., Hagarty, Devin, Mueller, Lauren E., Neve, Rachael L., Li, Jun-Xu, Chandra, Ramesh, Dietz, Karen C., Lobo, Mary Kay, Gancarz, Amy M., Yan, Zhen, Dietz, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742638/ https://www.ncbi.nlm.nih.gov/pubmed/31515501 http://dx.doi.org/10.1038/s41467-019-12122-8 |
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