Complete Genome Sequence of Herpes Simplex Virus 1 Strain MacIntyre

Herpes simplex virus type 1 (HSV-1) strain MacIntyre has a severe defect in the anterograde spread after replication in the nucleus. To better understand and identify the genetic determinants that lead to the unique phenotypes of the MacIntyre strain, we sequenced its genome with PacBio single-molec...

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Detalles Bibliográficos
Autores principales: Jiao, Xiaoli, Sui, Hongyan, Lyons, Christopher, Tran, Bao, Sherman, Brad T., Imamichi, Tomozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742799/
https://www.ncbi.nlm.nih.gov/pubmed/31515348
http://dx.doi.org/10.1128/MRA.00895-19
Descripción
Sumario:Herpes simplex virus type 1 (HSV-1) strain MacIntyre has a severe defect in the anterograde spread after replication in the nucleus. To better understand and identify the genetic determinants that lead to the unique phenotypes of the MacIntyre strain, we sequenced its genome with PacBio single-molecule real-time sequencing technology and resolved the complete sequence.

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