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Rhoptry and Dense Granule Secreted Effectors Regulate CD8(+) T Cell Recognition of Toxoplasma gondii Infected Host Cells

Toxoplasma gondii secretes rhoptry (ROP) and dense granule (GRA) effector proteins to evade host immune clearance mediated by interferon gamma (IFN-γ), immunity-related GTPase (IRG) effectors, and CD8(+) T cells. Here, we investigated the role of parasite-secreted effectors in regulating host access...

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Detalles Bibliográficos
Autores principales:	Rommereim, Leah M., Fox, Barbara A., Butler, Kiah L., Cantillana, Viviana, Taylor, Gregory A., Bzik, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742963/ https://www.ncbi.nlm.nih.gov/pubmed/31555296 http://dx.doi.org/10.3389/fimmu.2019.02104

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