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Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects
The apolipoprotein E gene (APOE) ε4 allele has a strong and manifold impact on cognition and neuroimaging phenotypes in cognitively normal subjects, including alterations in the white matter (WM) microstructure. Such alterations have often been regarded as a reflection of potential thinning of the m...
Autores principales: | Operto, Grégory, Molinuevo, José Luis, Cacciaglia, Raffaele, Falcon, Carles, Brugulat-Serrat, Anna, Suárez-Calvet, Marc, Grau-Rivera, Oriol, Bargalló, Nuria, Morán, Sebastián, Esteller, Manel, Gispert, Juan Domingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742967/ https://www.ncbi.nlm.nih.gov/pubmed/31520917 http://dx.doi.org/10.1016/j.nicl.2019.101983 |
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