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Efficacy and Long-term Peripheral Sensory Neuropathy of 3 vs 6 Months of Oxaliplatin-Based Adjuvant Chemotherapy for Colon Cancer: The ACHIEVE Phase 3 Randomized Clinical Trial

IMPORTANCE: Oxaliplatin-based chemotherapy is associated with debilitating peripheral sensory neuropathy (PSN) for patients with stage III colon cancer. OBJECTIVE: To assess disease-free survival (DFS) and long-lasting PSN in patients treated with 3 vs 6 months of adjuvant oxaliplatin-based chemothe...

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Detalles Bibliográficos
Autores principales: Yoshino, Takayuki, Yamanaka, Takeharu, Oki, Eiji, Kotaka, Masahito, Manaka, Dai, Eto, Tetsuya, Hasegawa, Junichi, Takagane, Akinori, Nakamura, Masato, Kato, Takeshi, Munemoto, Yoshinori, Takeuchi, Shintaro, Bando, Hiroyuki, Taniguchi, Hiroki, Gamoh, Makio, Shiozawa, Manabu, Mizushima, Tsunekazu, Saji, Shigetoyo, Maehara, Yoshihiko, Ohtsu, Atsushi, Mori, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743062/
https://www.ncbi.nlm.nih.gov/pubmed/31513248
http://dx.doi.org/10.1001/jamaoncol.2019.2572