The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients

OBJECTIVE: Staphylococcus aureus with the ability of biofilm formation and the drug resistance acquisition is one of the most frequently isolated pathogens from chronic rhinosinusitis patients. Ultrasound as an alternative therapy is effectively able to kill the bacteria by cavitation in or on the b...

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Autores principales: Feizabadi, Narjes, Sarrafzadeh, Javad, Fathali, Mojtaba, Vasaghi-Gharamaleki, Behnoosh, Dadgoo, Mahdi, Kardan-Yamchi, Jalil, Kazemian, Hossein, Hesam-Shariati, Sonia, Feizabadi, Mohammad Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743179/
https://www.ncbi.nlm.nih.gov/pubmed/31519221
http://dx.doi.org/10.1186/s13104-019-4579-3
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author Feizabadi, Narjes
Sarrafzadeh, Javad
Fathali, Mojtaba
Vasaghi-Gharamaleki, Behnoosh
Dadgoo, Mahdi
Kardan-Yamchi, Jalil
Kazemian, Hossein
Hesam-Shariati, Sonia
Feizabadi, Mohammad Mehdi
author_facet Feizabadi, Narjes
Sarrafzadeh, Javad
Fathali, Mojtaba
Vasaghi-Gharamaleki, Behnoosh
Dadgoo, Mahdi
Kardan-Yamchi, Jalil
Kazemian, Hossein
Hesam-Shariati, Sonia
Feizabadi, Mohammad Mehdi
author_sort Feizabadi, Narjes
collection PubMed
description OBJECTIVE: Staphylococcus aureus with the ability of biofilm formation and the drug resistance acquisition is one of the most frequently isolated pathogens from chronic rhinosinusitis patients. Ultrasound as an alternative therapy is effectively able to kill the bacteria by cavitation in or on the bacterial cells and peroxide generation and hence improving antibiotic treatment efficacy. RESULTS: Staphylococcus aureus was detected in 4 and 6 out of 14 patients by phenotypic and qPCR assays, respectively. Four patients were completely resolved after pulsed ultrasound treatment. However, presence of the S. aureus was confirmed in three healthy controls by bacterial cultivation. Pulsed ultrasound have been quantitatively decreased the S. aureus population in chronic rhinosinusitis patients (p < 0.05). Further studies need to be investigated the effectiveness of pulsed ultrasound as an alternative course of CRS patient’s treatment.
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spelling pubmed-67431792019-09-16 The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients Feizabadi, Narjes Sarrafzadeh, Javad Fathali, Mojtaba Vasaghi-Gharamaleki, Behnoosh Dadgoo, Mahdi Kardan-Yamchi, Jalil Kazemian, Hossein Hesam-Shariati, Sonia Feizabadi, Mohammad Mehdi BMC Res Notes Research Note OBJECTIVE: Staphylococcus aureus with the ability of biofilm formation and the drug resistance acquisition is one of the most frequently isolated pathogens from chronic rhinosinusitis patients. Ultrasound as an alternative therapy is effectively able to kill the bacteria by cavitation in or on the bacterial cells and peroxide generation and hence improving antibiotic treatment efficacy. RESULTS: Staphylococcus aureus was detected in 4 and 6 out of 14 patients by phenotypic and qPCR assays, respectively. Four patients were completely resolved after pulsed ultrasound treatment. However, presence of the S. aureus was confirmed in three healthy controls by bacterial cultivation. Pulsed ultrasound have been quantitatively decreased the S. aureus population in chronic rhinosinusitis patients (p < 0.05). Further studies need to be investigated the effectiveness of pulsed ultrasound as an alternative course of CRS patient’s treatment. BioMed Central 2019-09-13 /pmc/articles/PMC6743179/ /pubmed/31519221 http://dx.doi.org/10.1186/s13104-019-4579-3 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Feizabadi, Narjes
Sarrafzadeh, Javad
Fathali, Mojtaba
Vasaghi-Gharamaleki, Behnoosh
Dadgoo, Mahdi
Kardan-Yamchi, Jalil
Kazemian, Hossein
Hesam-Shariati, Sonia
Feizabadi, Mohammad Mehdi
The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients
title The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients
title_full The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients
title_fullStr The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients
title_full_unstemmed The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients
title_short The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients
title_sort pulsed ultrasound strategy effectively decreases the s. aureus population of chronic rhinosinusitis patients
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743179/
https://www.ncbi.nlm.nih.gov/pubmed/31519221
http://dx.doi.org/10.1186/s13104-019-4579-3
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