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Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment

BACKGROUND: Skin cutaneous melanoma (SKCM) is the most lethal form of skin cancer and while incidence rates are declining for most cancers, they have been steadily rising for SKCM. Serine protease inhibitor, kunitz-type, 1 (SPINT1) is a type II transmembrane serine protease inhibitor that has been s...

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Detalles Bibliográficos
Autores principales:	Gómez-Abenza, Elena, Ibáñez-Molero, Sofía, García-Moreno, Diana, Fuentes, Inmaculada, Zon, Leonard I., Mione, Maria C., Cayuela, María L., Gabellini, Chiara, Mulero, Victoriano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743187/ https://www.ncbi.nlm.nih.gov/pubmed/31519199 http://dx.doi.org/10.1186/s13046-019-1389-3

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