Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells

Corneal endothelial tissue engineering aims to find solutions for blindness due to endothelial dysfunction. A suitable combination of endothelial cells, substrates and environmental cues should be deployed for engineering functional endothelial tissues. This manuscript reviews up-to-date topics of c...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Qin, Sun, Hong, Yang, Dongmei, Tighe, Sean, Liu, Yongsong, Zhu, Yingting, Hu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743271/
https://www.ncbi.nlm.nih.gov/pubmed/31523168
http://dx.doi.org/10.7150/ijms.34440
_version_ 1783451253978693632
author Zhu, Qin
Sun, Hong
Yang, Dongmei
Tighe, Sean
Liu, Yongsong
Zhu, Yingting
Hu, Min
author_facet Zhu, Qin
Sun, Hong
Yang, Dongmei
Tighe, Sean
Liu, Yongsong
Zhu, Yingting
Hu, Min
author_sort Zhu, Qin
collection PubMed
description Corneal endothelial tissue engineering aims to find solutions for blindness due to endothelial dysfunction. A suitable combination of endothelial cells, substrates and environmental cues should be deployed for engineering functional endothelial tissues. This manuscript reviews up-to-date topics of corneal endothelial tissue engineering with special emphasis on biomaterial substrates and their properties, efficacy, and mechanisms of supporting functional endothelial cells in vitro.
format Online
Article
Text
id pubmed-6743271
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Ivyspring International Publisher
record_format MEDLINE/PubMed
spelling pubmed-67432712019-09-13 Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells Zhu, Qin Sun, Hong Yang, Dongmei Tighe, Sean Liu, Yongsong Zhu, Yingting Hu, Min Int J Med Sci Review Corneal endothelial tissue engineering aims to find solutions for blindness due to endothelial dysfunction. A suitable combination of endothelial cells, substrates and environmental cues should be deployed for engineering functional endothelial tissues. This manuscript reviews up-to-date topics of corneal endothelial tissue engineering with special emphasis on biomaterial substrates and their properties, efficacy, and mechanisms of supporting functional endothelial cells in vitro. Ivyspring International Publisher 2019-07-21 /pmc/articles/PMC6743271/ /pubmed/31523168 http://dx.doi.org/10.7150/ijms.34440 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Zhu, Qin
Sun, Hong
Yang, Dongmei
Tighe, Sean
Liu, Yongsong
Zhu, Yingting
Hu, Min
Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells
title Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells
title_full Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells
title_fullStr Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells
title_full_unstemmed Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells
title_short Cellular Substrates for Cell-Based Tissue Engineering of Human Corneal Endothelial Cells
title_sort cellular substrates for cell-based tissue engineering of human corneal endothelial cells
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743271/
https://www.ncbi.nlm.nih.gov/pubmed/31523168
http://dx.doi.org/10.7150/ijms.34440
work_keys_str_mv AT zhuqin cellularsubstratesforcellbasedtissueengineeringofhumancornealendothelialcells
AT sunhong cellularsubstratesforcellbasedtissueengineeringofhumancornealendothelialcells
AT yangdongmei cellularsubstratesforcellbasedtissueengineeringofhumancornealendothelialcells
AT tighesean cellularsubstratesforcellbasedtissueengineeringofhumancornealendothelialcells
AT liuyongsong cellularsubstratesforcellbasedtissueengineeringofhumancornealendothelialcells
AT zhuyingting cellularsubstratesforcellbasedtissueengineeringofhumancornealendothelialcells
AT humin cellularsubstratesforcellbasedtissueengineeringofhumancornealendothelialcells

Ejemplares similares