Exosomes derived from Wharton's jelly of human umbilical cord mesenchymal stem cells reduce osteocyte apoptosis in glucocorticoid-induced osteonecrosis of the femoral head in rats via the miR-21-PTEN-AKT signalling pathway

Purpose: Glucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is a common disease after long-term or high-dose glucocorticoid use. The pathogenesis of GIONFH is still controversial, and abnormal bone metabolism caused by glucocorticoids may be one of the important factors. Exosomes, owi...

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Detalles Bibliográficos
Autores principales: Kuang, Ming-jie, Huang, Ying, Zhao, Xi-ge, Zhang, Rui, Ma, Jian-xiong, Wang, Da-chuan, Ma, Xin-long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743291/
https://www.ncbi.nlm.nih.gov/pubmed/31523188
http://dx.doi.org/10.7150/ijbs.32262

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