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p53 Mutant p53(N236S) Induces Neural Tube Defects in Female Embryos
The p53 is one of the most important tumor suppressors through surveillance of DNA damages and abnormal proliferation signals, and activation the cell cycle arrest and apoptosis in response to stress. However, the mutation of p53 is known to be oncogenic by both loss of function in inhibiting cell c...
Autores principales: | Zhao, Jinzhi, Tian, Yingbing, Zhang, Huihui, Qu, Lianhua, Chen, Yu, Liu, Qing, Luo, Ying, Wu, Xiaoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743294/ https://www.ncbi.nlm.nih.gov/pubmed/31523200 http://dx.doi.org/10.7150/ijbs.31451 |
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