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Melatonin Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib through the PERK-ATF4-Beclin1 Pathway

The mechanisms of resistance to the targeted drug sorafenib in the treatment of hepatocellular carcinoma (HCC) are poorly understood. The purpose of this study was to investigate the mechanism of sorafenib resistance and to elucidate the role of melatonin in overcoming sorafenib resistance. We first...

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Detalles Bibliográficos
Autores principales:	Zhou, Bei, Lu, Qianqian, Liu, Jiatao, Fan, Lulu, Wang, Yu, Wei, Wei, Wang, Hua, Sun, Guoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743299/ https://www.ncbi.nlm.nih.gov/pubmed/31523192 http://dx.doi.org/10.7150/ijbs.32550

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