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Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice

Sepsis is one of the most prevalent diseases in the world. The development of cardiac dysfunction in sepsis results in an increase of mortality. It is known that Bruton's tyrosine kinase (BTK) plays a role in toll-like receptor signaling and NLRP3 inflammasome activation, two key components in...

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Detalles Bibliográficos
Autores principales: O'Riordan, Caroline E., Purvis, Gareth S. D., Collotta, Debora, Chiazza, Fausto, Wissuwa, Bianka, Al Zoubi, Sura, Stiehler, Lara, Martin, Lukas, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743418/
https://www.ncbi.nlm.nih.gov/pubmed/31552054
http://dx.doi.org/10.3389/fimmu.2019.02129