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Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice
Sepsis is one of the most prevalent diseases in the world. The development of cardiac dysfunction in sepsis results in an increase of mortality. It is known that Bruton's tyrosine kinase (BTK) plays a role in toll-like receptor signaling and NLRP3 inflammasome activation, two key components in...
Autores principales: | O'Riordan, Caroline E., Purvis, Gareth S. D., Collotta, Debora, Chiazza, Fausto, Wissuwa, Bianka, Al Zoubi, Sura, Stiehler, Lara, Martin, Lukas, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743418/ https://www.ncbi.nlm.nih.gov/pubmed/31552054 http://dx.doi.org/10.3389/fimmu.2019.02129 |
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