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Risk assessment of FLT3 and PAX5 variants in B-acute lymphoblastic leukemia: a case–control study in a Pakistani cohort

AIMS: B-cell acute lymphoblastic leukemia (B-ALL) is amongst the most prevalent cancers of children in Pakistan. Genetic variations in FLT3 are associated with auto-phosphorylation of kinase domain that leads to increased proliferation of blast cells. Paired box family of transcription factor (PAX5)...

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Detalles Bibliográficos
Autores principales: Khalid, Ammara, Aslam, Sara, Ahmed, Mehboob, Hasnain, Shahida, Aslam, Aimen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743442/
https://www.ncbi.nlm.nih.gov/pubmed/31565544
http://dx.doi.org/10.7717/peerj.7195