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PCR-free whole exome sequencing: Cost-effective and efficient in detecting rare mutations
In this study, we describe the development of a PCR-free whole exome sequencing method. Using this method, 2 μg DNA was sufficient for library preparation for whole exome sequencing. Furthermore, the method is simple and makes use of a commercial kit, with additional step of concentrating the captur...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743761/ https://www.ncbi.nlm.nih.gov/pubmed/31518370 http://dx.doi.org/10.1371/journal.pone.0222562 |