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Changes in chromatin accessibility ensure robust cell cycle exit in terminally differentiated cells
During terminal differentiation, most cells exit the cell cycle and enter into a prolonged or permanent G0 in which they are refractory to mitogenic signals. Entry into G0 is usually initiated through the repression of cell cycle gene expression by formation of a transcriptional repressor complex ca...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743789/ https://www.ncbi.nlm.nih.gov/pubmed/31479438 http://dx.doi.org/10.1371/journal.pbio.3000378 |