Cargando…
Executable pathway analysis using ensemble discrete-state modeling for large-scale data
Pathway analysis is widely used to gain mechanistic insights from high-throughput omics data. However, most existing methods do not consider signal integration represented by pathway topology, resulting in enrichment of convergent pathways when downstream genes are modulated. Incorporation of signal...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743792/ https://www.ncbi.nlm.nih.gov/pubmed/31479446 http://dx.doi.org/10.1371/journal.pcbi.1007317 |