Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons

Bardet-Biedl syndrome (BBS), a ciliopathy, is a rare genetic condition characterised by retinal degeneration, obesity, kidney failure, and cognitive impairment. In spite of progress made in our general understanding of BBS aetiology, the molecular and cellular mechanisms underlying cognitive impairm...

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Detalles Bibliográficos
Autores principales: Haq, Naila, Schmidt-Hieber, Christoph, Sialana, Fernando J., Ciani, Lorenza, Heller, Janosch P., Stewart, Michelle, Bentley, Liz, Wells, Sara, Rodenburg, Richard J., Nolan, Patrick M., Forsythe, Elizabeth, Wu, Michael C., Lubec, Gert, Salinas, P., Häusser, Michael, Beales, Philip L., Christou-Savina, Sofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743795/
https://www.ncbi.nlm.nih.gov/pubmed/31479441
http://dx.doi.org/10.1371/journal.pbio.3000414

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