Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study

BACKGROUND: Midlife hypertension confers increased risk for cognitive impairment in late life. The sensitive period for risk exposure and extent that risk is mediated through amyloid or vascular-related mechanisms are poorly understood. We aimed to identify if, and when, blood pressure or change in...

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Detalles Bibliográficos
Autores principales: Lane, Christopher A, Barnes, Josephine, Nicholas, Jennifer M, Sudre, Carole H, Cash, David M, Parker, Thomas D, Malone, Ian B, Lu, Kirsty, James, Sarah-Naomi, Keshavan, Ashvini, Murray-Smith, Heidi, Wong, Andrew, Buchanan, Sarah M, Keuss, Sarah E, Gordon, Elizabeth, Coath, William, Barnes, Anna, Dickson, John, Modat, Marc, Thomas, David, Crutch, Sebastian J, Hardy, Rebecca, Richards, Marcus, Fox, Nick C, Schott, Jonathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744368/
https://www.ncbi.nlm.nih.gov/pubmed/31444142
http://dx.doi.org/10.1016/S1474-4422(19)30228-5

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