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Identification of Sialic Acid Linkages on Intact Glycopeptides via Differential Chemical Modification Using IntactGIG-HILIC

Mass spectrometric analysis of intact glycopeptides can reveal detailed information about glycosite, glycan structural features, and their heterogeneity. Sialyl glycopeptides can be positively, negatively, or neutrally charged depending on pH of their buffer solution and ionization conditions. To de...

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Detalles Bibliográficos
Autores principales: Yang, Shuang, Wu, Wells W., Shen, Rong-Fong, Bern, Marshall, Cipollo, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744383/
https://www.ncbi.nlm.nih.gov/pubmed/29651731
http://dx.doi.org/10.1007/s13361-018-1931-0