Cargando…
Focal Adhesion Kinase Inhibition Contributes to Tumor Cell Survival and Motility in Neuroblastoma Patient-Derived Xenografts
Patient-derived xenografts (PDXs) provide an opportunity to evaluate the effects of therapies in an environment that more closely resembles the human condition than that seen with long-term passage cell lines. In the current studies, we investigated the effects of FAK inhibition on two neuroblastoma...
Autores principales: | Stafman, Laura L., Williams, Adele P., Marayati, Raoud, Aye, Jamie M., Markert, Hooper R., Garner, Evan F., Quinn, Colin H., Lallani, Shoeb B., Stewart, Jerry E., Yoon, Karina J., Whelan, Kimberly, Beierle, Elizabeth A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744403/ https://www.ncbi.nlm.nih.gov/pubmed/31519958 http://dx.doi.org/10.1038/s41598-019-49853-z |
Ejemplares similares
-
9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts
por: Marayati, Raoud, et al.
Publicado: (2020) -
EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth
por: Bownes, Laura V., et al.
Publicado: (2021) -
Targeting High-Risk Neuroblastoma Patient-Derived Xenografts with Oncolytic Virotherapy
por: Quinn, Colin H., et al.
Publicado: (2022) -
The effects of focal adhesion kinase and platelet-derived growth factor receptor beta inhibition in a patient-derived xenograft model of primary and metastatic Wilms tumor
por: Aye, Jamie M., et al.
Publicado: (2019) -
Investigation of PP2A and Its Endogenous Inhibitors in Neuroblastoma Cell Survival and Tumor Growth
por: Williams, Adele P., et al.
Publicado: (2018)