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Cryo-EM structures of lipopolysaccharide transporter LptB(2)FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism
Lipopolysaccharides (LPS) of Gram-negative bacteria are critical for the defence against cytotoxic substances and must be transported from the inner membrane (IM) to the outer membrane (OM) through a bridge formed by seven membrane proteins (LptBFGCADE). The IM component LptB(2)FG powers the process...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744409/ https://www.ncbi.nlm.nih.gov/pubmed/31519889 http://dx.doi.org/10.1038/s41467-019-11977-1 |