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HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs
Maintenance of high-turnover tissues such as the epidermis requires a balance between stem cell proliferation and differentiation. The molecular mechanisms governing this process are an area of investigation. Here we show that HNRNPK, a multifunctional protein, is necessary to prevent premature diff...
Autores principales: | Li, Jingting, Chen, Yifang, Xu, Xiaojun, Jones, Jackson, Tiwari, Manisha, Ling, Ji, Wang, Ying, Harismendy, Olivier, Sen, George L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744489/ https://www.ncbi.nlm.nih.gov/pubmed/31519929 http://dx.doi.org/10.1038/s41467-019-12238-x |
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