Activated α(2)-Macroglobulin Regulates LRP1 Levels at the Plasma Membrane through the Activation of a Rab10-dependent Exocytic Pathway in Retinal Müller Glial Cells

Activated α(2)-macroglobulin (α(2)M*) and its receptor, low-density lipoprotein receptor-related protein 1 (LRP1), have been linked to proliferative retinal diseases. In Müller glial cells (MGCs), the α(2)M*/LRP1 interaction induces cell signaling, cell migration, and extracellular matrix remodeling...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaldín-Fincati, Javier R., Actis Dato, Virginia, Díaz, Nicolás M., Sánchez, María C., Barcelona, Pablo F., Chiabrando, Gustavo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744500/
https://www.ncbi.nlm.nih.gov/pubmed/31519919
http://dx.doi.org/10.1038/s41598-019-49072-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744500/
https://www.ncbi.nlm.nih.gov/pubmed/31519919
http://dx.doi.org/10.1038/s41598-019-49072-6

Ejemplares similares