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A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report

BACKGROUND: Solitary fibrous tumor (SFT) is a rare mesenchymal tumor that typically arises from the pleura. Although it may appear in other organs, it rarely develops in the pancreas. We report herein a rare case of metastatic SFT of the pancreas originating from an intracranial tumor and subsequent...

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Autores principales: Yamashita, Hironori, Fujino, Yasuhiro, Ohara, Tadayuki, Kakinoki, Keitaro, Sugimoto, Takemi, Kajimoto, Kazuyoshi, Tominaga, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744537/
https://www.ncbi.nlm.nih.gov/pubmed/31520184
http://dx.doi.org/10.1186/s40792-019-0699-1
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author Yamashita, Hironori
Fujino, Yasuhiro
Ohara, Tadayuki
Kakinoki, Keitaro
Sugimoto, Takemi
Kajimoto, Kazuyoshi
Tominaga, Masahiro
author_facet Yamashita, Hironori
Fujino, Yasuhiro
Ohara, Tadayuki
Kakinoki, Keitaro
Sugimoto, Takemi
Kajimoto, Kazuyoshi
Tominaga, Masahiro
author_sort Yamashita, Hironori
collection PubMed
description BACKGROUND: Solitary fibrous tumor (SFT) is a rare mesenchymal tumor that typically arises from the pleura. Although it may appear in other organs, it rarely develops in the pancreas. We report herein a rare case of metastatic SFT of the pancreas originating from an intracranial tumor and subsequently identified as a cystic neoplasm of the pancreas. CASE PRESENTATION: A 58-year-old woman with a past medical history of brain tumor visited the hospital for further investigation of a cystic tumor in the pancreas tail. Abdominal imaging showed a heterogeneously enhancing mass that was initially suspected as a neuroendocrine neoplasm, solid pseudopapillary neoplasm, or mucinous cystic neoplasm of the pancreas. Distal pancreatectomy was performed without any intraoperative and postoperative complications. Pathological findings confirmed a diagnosis of malignant SFT of the pancreas with hyperproliferative potential. A histopathological review of her brain tumor revealed that the pancreatic tumor was derived from her brain lesion. The patient developed recurrent brain disease 4 years after the pancreatectomy, but no recurrence has been observed in the abdominal cavity. CONCLUSIONS: SFT should be considered in the differential diagnosis of untypical hypervascular pancreatic mass, particularly in patients with a history of an intrathoracic or intracranial mesenchymal tumor. Immunohistochemical analysis is crucial in detecting this tumor entity. Hyperproliferative status indicates a malignant disease and requires careful postoperative observation.
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spelling pubmed-67445372019-09-27 A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report Yamashita, Hironori Fujino, Yasuhiro Ohara, Tadayuki Kakinoki, Keitaro Sugimoto, Takemi Kajimoto, Kazuyoshi Tominaga, Masahiro Surg Case Rep Case Report BACKGROUND: Solitary fibrous tumor (SFT) is a rare mesenchymal tumor that typically arises from the pleura. Although it may appear in other organs, it rarely develops in the pancreas. We report herein a rare case of metastatic SFT of the pancreas originating from an intracranial tumor and subsequently identified as a cystic neoplasm of the pancreas. CASE PRESENTATION: A 58-year-old woman with a past medical history of brain tumor visited the hospital for further investigation of a cystic tumor in the pancreas tail. Abdominal imaging showed a heterogeneously enhancing mass that was initially suspected as a neuroendocrine neoplasm, solid pseudopapillary neoplasm, or mucinous cystic neoplasm of the pancreas. Distal pancreatectomy was performed without any intraoperative and postoperative complications. Pathological findings confirmed a diagnosis of malignant SFT of the pancreas with hyperproliferative potential. A histopathological review of her brain tumor revealed that the pancreatic tumor was derived from her brain lesion. The patient developed recurrent brain disease 4 years after the pancreatectomy, but no recurrence has been observed in the abdominal cavity. CONCLUSIONS: SFT should be considered in the differential diagnosis of untypical hypervascular pancreatic mass, particularly in patients with a history of an intrathoracic or intracranial mesenchymal tumor. Immunohistochemical analysis is crucial in detecting this tumor entity. Hyperproliferative status indicates a malignant disease and requires careful postoperative observation. Springer Berlin Heidelberg 2019-09-13 /pmc/articles/PMC6744537/ /pubmed/31520184 http://dx.doi.org/10.1186/s40792-019-0699-1 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Case Report
Yamashita, Hironori
Fujino, Yasuhiro
Ohara, Tadayuki
Kakinoki, Keitaro
Sugimoto, Takemi
Kajimoto, Kazuyoshi
Tominaga, Masahiro
A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report
title A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report
title_full A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report
title_fullStr A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report
title_full_unstemmed A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report
title_short A rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report
title_sort rare case of metastatic solitary fibrous tumor of the pancreas manifesting as a cystic neoplasm: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744537/
https://www.ncbi.nlm.nih.gov/pubmed/31520184
http://dx.doi.org/10.1186/s40792-019-0699-1
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