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Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development

BACKGROUND: Single nucleotide polymorphisms (SNPs) in genes encoding mitotic kinases could influence development and progression of gastric cancer (GC). METHODS: Case-control study of nine SNPs in mitotic genes was conducted using qPCR. The study included 116 GC patients and 203 controls. In silico...

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Detalles Bibliográficos
Autores principales: Mesic, Aner, Rogar, Marija, Hudler, Petra, Bilalovic, Nurija, Eminovic, Izet, Komel, Radovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744709/
https://www.ncbi.nlm.nih.gov/pubmed/31521144
http://dx.doi.org/10.1186/s12885-019-6133-z