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Quantitative Insights into Age-Associated DNA-Repair Inefficiency in Single Cells
Although double-strand break (DSB) repair is essential for a cell’s survival, little is known about how DSB repair mechanisms are affected by age. Here we characterize the impact of cellular aging on the efficiency of single-strand annealing (SSA), a DSB repair mechanism. We measure SSA repair effic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744837/ https://www.ncbi.nlm.nih.gov/pubmed/31433994 http://dx.doi.org/10.1016/j.celrep.2019.07.082 |