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Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction

Reactive oxygen species (ROS) play important roles in aging, inflammation, and cancer. Mitochondria are an important source of ROS; however, the spatiotemporal ROS events underlying oxidative cellular damage from dysfunctional mitochondria remain unresolved. To this end, we have developed and valida...

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Detalles Bibliográficos
Autores principales: Qian, Wei, Kumar, Namrata, Roginskaya, Vera, Fouquerel, Elise, Opresko, Patricia L., Shiva, Sruti, Watkins, Simon C., Kolodieznyi, Dmytro, Bruchez, Marcel P., Van Houten, Bennett
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744920/
https://www.ncbi.nlm.nih.gov/pubmed/31451640
http://dx.doi.org/10.1073/pnas.1910574116