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Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction
Reactive oxygen species (ROS) play important roles in aging, inflammation, and cancer. Mitochondria are an important source of ROS; however, the spatiotemporal ROS events underlying oxidative cellular damage from dysfunctional mitochondria remain unresolved. To this end, we have developed and valida...
Autores principales: | Qian, Wei, Kumar, Namrata, Roginskaya, Vera, Fouquerel, Elise, Opresko, Patricia L., Shiva, Sruti, Watkins, Simon C., Kolodieznyi, Dmytro, Bruchez, Marcel P., Van Houten, Bennett |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744920/ https://www.ncbi.nlm.nih.gov/pubmed/31451640 http://dx.doi.org/10.1073/pnas.1910574116 |
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