Histone Acetyltransferase-Dependent Pathways Mediate Upregulation of NADPH Oxidase 5 in Human Macrophages under Inflammatory Conditions: A Potential Mechanism of Reactive Oxygen Species Overproduction in Atherosclerosis

Histone acetylation plays a major role in epigenetic regulation of gene expression. Monocyte-derived macrophages express functional NADPH oxidase 5 (Nox5) that contributes to oxidative stress in atherogenesis. The mechanisms of Nox5 regulation are not entirely elucidated. The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Vlad, Mihaela-Loredana, Manea, Simona-Adriana, Lazar, Alexandra-Gela, Raicu, Monica, Muresian, Horia, Simionescu, Maya, Manea, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745143/
https://www.ncbi.nlm.nih.gov/pubmed/31565149
http://dx.doi.org/10.1155/2019/3201062

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