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Amplification and attenuation of lung metastases depending on glucocorticoid dosage implicating long‐acting activated memory cells induced by nivolumab against malignant melanoma
Firstly, glucocorticoids such as prednisolone can attenuate the effect of anti–PD‐1 antibody nivolumab. Secondly, malignant melanoma cells survived latently and unnoticeably in places other than those of previous metastatic lesions. Thirdly, effector T cells activated by nivolumab sustained their me...
Autores principales: | Katagiri, Katsunori, Shiga, Kiyoto, Saito, Daisuke, Oikawa, Shin‐ichi, Ikeda, Aya, Tsuchida, Kodai, Miyaguchi, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745446/ https://www.ncbi.nlm.nih.gov/pubmed/31534732 http://dx.doi.org/10.1002/ccr3.2349 |
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