Rectal cancer sub-clones respond differentially to neoadjuvant therapy()

Treatment of locally advanced rectal cancer includes chemotherapy, radiation, and surgery but patient responses to neoadjuvant treatment are variable. We have shown that rectal tumors are comprised of multiple genetically distinct sub-clones. Unique sub-clones within tumors may harbor mutations whic...

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Detalles Bibliográficos
Autores principales: Frydrych, Lynn M, Ulintz, Peter, Bankhead, Armand, Sifuentes, Christopher, Greenson, Joel, Maguire, Lillias, Irwin, Regina, Fearon, Eric R., Hardiman, Karin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745489/
https://www.ncbi.nlm.nih.gov/pubmed/31521947
http://dx.doi.org/10.1016/j.neo.2019.08.004

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