Dietary sulfur amino acid restriction upregulates DICER to confer beneficial effects

OBJECTIVE: Dietary restriction (DR) improves health and prolongs lifespan in part by upregulating type III endoribonuclease DICER in adipose tissue. In this study, we aimed to specifically test which missing dietary component was responsible for DICER upregulation. METHODS: We performed a nutrient s...

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Detalles Bibliográficos
Autores principales: Guerra, Beatriz A., Brandão, Bruna B., Pinto, Silas S., Salgueiro, Willian G., De-Souza, Evandro A., Reis, Felipe C.G., Batista, Thiago M., Cavalcante-Silva, Vanessa, D'Almeida, Vânia, Castilho, Beatriz A., Carneiro, Everardo M., Antebi, Adam, Festuccia, William T., Mori, Marcelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745493/
https://www.ncbi.nlm.nih.gov/pubmed/31668384
http://dx.doi.org/10.1016/j.molmet.2019.08.017

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