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The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification

Krüppel‐associated box (KRAB)‐containing zinc finger proteins (KZFPs) are encoded in the hundreds by the genomes of higher vertebrates, and many act with the heterochromatin‐inducing KAP1 as repressors of transposable elements (TEs) during early embryogenesis. Yet, their widespread expression in adu...

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Detalles Bibliográficos
Autores principales: Helleboid, Pierre‐Yves, Heusel, Moritz, Duc, Julien, Piot, Cécile, Thorball, Christian W, Coluccio, Andrea, Pontis, Julien, Imbeault, Michaël, Turelli, Priscilla, Aebersold, Ruedi, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745500/
https://www.ncbi.nlm.nih.gov/pubmed/31403225
http://dx.doi.org/10.15252/embj.2018101220

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