Minimizing control group allocation in randomized trials using dynamic borrowing of external control data – An application to second line therapy for non-small cell lung cancer

BACKGROUND: Enrollment of participants to control arms in clinical trials can be challenging. This is particularly an issue in oncology trials where the standard-of-care is shifting rapidly and several promising experimental treatments are undergoing phase III testing. Novel methods for utilizing ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Dron, Louis, Golchi, Shirin, Hsu, Grace, Thorlund, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745532/
https://www.ncbi.nlm.nih.gov/pubmed/31538129
http://dx.doi.org/10.1016/j.conctc.2019.100446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745532/
https://www.ncbi.nlm.nih.gov/pubmed/31538129
http://dx.doi.org/10.1016/j.conctc.2019.100446

Ejemplares similares