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In Vitro and in Vivo antitumor activity and the mechanism of siphonodictyal B in human colon cancer cells

Liphagal, isolated from the marine sponge Aka coralliphaga, exhibits phosphatidylinositol 3‐kinase alpha (PI3Kα) inhibitory activity and cytotoxic effects in human cancer cells. Siphonodictyal B, the biogenetic precursor of liphagal, also has PI3K inhibitory activity. However, its cytotoxic or antit...

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Detalles Bibliográficos
Autores principales:	Chikamatsu, Sonoko, Saijo, Ken, Imai, Hiroo, Narita, Koichi, Kawamura, Yoshifumi, Katoh, Tadashi, Ishioka, Chikashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745845/ https://www.ncbi.nlm.nih.gov/pubmed/31364822 http://dx.doi.org/10.1002/cam4.2409

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