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Germline mismatch repair gene variants analyzed by universal sequencing in Japanese cancer patients

BACKGROUND: Lynch syndrome (LS) is the commonest inherited cancer syndrome caused by pathogenic variants of germline DNA mismatch repair (g.MMR) genes. Genome‐wide sequencing is now increasingly applied for tumor characterization, but not for g.MMR. The aim of this study was to evaluate the incidenc...

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Detalles Bibliográficos
Autores principales:	Kiyozumi, Yoshimi, Matsubayashi, Hiroyuki, Horiuchi, Yasue, Higashigawa, Satomi, Oishi, Takuma, Abe, Masato, Ohnami, Sumiko, Urakami, Kenichi, Nagashima, Takeshi, Kusuhara, Masatoshi, Miyake, Hidehiko, Yamaguchi, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745857/ https://www.ncbi.nlm.nih.gov/pubmed/31386297 http://dx.doi.org/10.1002/cam4.2432

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