Development of Pyridine-based Inhibitors for the Human Vaccinia-related Kinases 1 and 2

[Image: see text] Vaccinia-related kinases 1 and 2 (VRK1 and VRK2) are human Ser/Thr protein kinases associated with increased cell division and neurological disorders. Nevertheless, the cellular functions of these proteins are not fully understood. Despite their therapeutic potential, there are no...

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Detalles Bibliográficos
Autores principales: Serafim, Ricardo A. M., de Souza Gama, Fernando H., Dutra, Luiz A., dos Reis, Caio V., Vasconcelos, Stanley N. S., da Silva Santiago, André, Takarada, Jéssica E., Di Pillo, Fúlvia, Azevedo, Hatylas, Mascarello, Alessandra, Elkins, Jonathan M., Massirer, Katlin B., Gileadi, Opher, Guimarães, Cristiano R. W., Couñago, Rafael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746079/
https://www.ncbi.nlm.nih.gov/pubmed/31531195
http://dx.doi.org/10.1021/acsmedchemlett.9b00082

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