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Towards a Better Understanding of Cohesin Mutations in AML

Classical driver mutations in acute myeloid leukemia (AML) typically affect regulators of cell proliferation, differentiation, and survival. The selective advantage of increased proliferation, improved survival, and reduced differentiation on leukemia progression is immediately obvious. Recent large...

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Detalles Bibliográficos
Autores principales: Cuartero, Sergi, Innes, Andrew J., Merkenschlager, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746210/
https://www.ncbi.nlm.nih.gov/pubmed/31552185
http://dx.doi.org/10.3389/fonc.2019.00867

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