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Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism

Congenital hyperinsulinism (CHI) is characterised by inappropriate insulin secretion causing profound hypoglycaemia and brain damage if inadequately controlled. Pancreatic tissue isolated from patients with diffuse CHI shows abnormal proliferation rates, the mechanisms of which are not fully resolve...

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Detalles Bibliográficos
Autores principales:	Kellaway, Sophie G., Mosinska, Karolina, Mohamed, Zainaba, Ryan, Alexander, Richardson, Stephen, Newbould, Melanie, Banerjee, Indraneel, Dunne, Mark J., Cosgrove, Karen E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746350/ https://www.ncbi.nlm.nih.gov/pubmed/31525223 http://dx.doi.org/10.1371/journal.pone.0222350

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