Transcriptional profiling of single fiber cells in a transgenic paradigm of an inherited childhood cataract reveals absence of molecular heterogeneity

Our recent single-cell transcriptomic analysis has demonstrated that heterogeneous transcriptional activity attends molecular transition from the nascent to terminally differentiated fiber cells in the developing mouse lens. To understand the role of transcriptional heterogeneity in terminal differe...

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Detalles Bibliográficos
Autores principales: Bhat, Suraj P., Gangalum, Rajendra K., Kim, Dongjae, Mangul, Serghei, Kashyap, Raj K., Zhou, Xinkai, Elashoff, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746439/
https://www.ncbi.nlm.nih.gov/pubmed/31243103
http://dx.doi.org/10.1074/jbc.RA119.008853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746439/
https://www.ncbi.nlm.nih.gov/pubmed/31243103
http://dx.doi.org/10.1074/jbc.RA119.008853

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