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Expansion of base excision repair compensates for a lack of DNA repair by oxidative dealkylation in budding yeast

The Mag1 and Tpa1 proteins from budding yeast (Saccharomyces cerevisiae) have both been reported to repair alkylation damage in DNA. Mag1 initiates the base excision repair pathway by removing alkylated bases from DNA, and Tpa1 has been proposed to directly repair alkylated bases as does the prototy...

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Detalles Bibliográficos
Autores principales:	Admiraal, Suzanne J., Eyler, Daniel E., Baldwin, Michael R., Brines, Emily M., Lohans, Christopher T., Schofield, Christopher J., O'Brien, Patrick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	DNA and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746446/ https://www.ncbi.nlm.nih.gov/pubmed/31320474 http://dx.doi.org/10.1074/jbc.RA119.009813

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