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A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence

Coronaviruses are enveloped, single-stranded RNA viruses that are distributed worldwide. They include transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV), and the human coronaviruses severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory s...

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Detalles Bibliográficos
Autores principales: Shen, Zhou, Wang, Gang, Yang, Yiling, Shi, Jiale, Fang, Liurong, Li, Fang, Xiao, Shaobo, Fu, Zhen F., Peng, Guiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746460/
https://www.ncbi.nlm.nih.gov/pubmed/31350335
http://dx.doi.org/10.1074/jbc.RA119.009713