Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature

Acute promyelocytic leukemia (APL) in human immunodeficiency virus (HIV)-infected individuals is very rare. There is currently no consensus regarding the use of anti-cancer drugs with highly active anti-retroviral therapy (ART) in these patients due to their small number. We herein report two cases...

Descripción completa

Detalles Bibliográficos
Autores principales: Kunitomi, Akane, Hasegawa, Yuta, lmamura, Junji, Yokomaku, Yoshiyuki, Tokunaga, Takashi, Miyata, Yasuhiko, Iida, Hiroatsu, Nagai, Hirokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746639/
https://www.ncbi.nlm.nih.gov/pubmed/31118366
http://dx.doi.org/10.2169/internalmedicine.1662-18
_version_ 1783451718968672256
author Kunitomi, Akane
Hasegawa, Yuta
lmamura, Junji
Yokomaku, Yoshiyuki
Tokunaga, Takashi
Miyata, Yasuhiko
Iida, Hiroatsu
Nagai, Hirokazu
author_facet Kunitomi, Akane
Hasegawa, Yuta
lmamura, Junji
Yokomaku, Yoshiyuki
Tokunaga, Takashi
Miyata, Yasuhiko
Iida, Hiroatsu
Nagai, Hirokazu
author_sort Kunitomi, Akane
collection PubMed
description Acute promyelocytic leukemia (APL) in human immunodeficiency virus (HIV)-infected individuals is very rare. There is currently no consensus regarding the use of anti-cancer drugs with highly active anti-retroviral therapy (ART) in these patients due to their small number. We herein report two cases of APL with HIV-infected patients. Both cases received all-trans-retinoic acid-containing chemotherapies and achieved complete remission. ART was continued throughout the treatment course. The clinical course of these cases suggests that it is preferable to perform standard chemotherapy for APL with ART if patients have an adequate performance status.
format Online
Article
Text
id pubmed-6746639
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-67466392019-09-17 Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature Kunitomi, Akane Hasegawa, Yuta lmamura, Junji Yokomaku, Yoshiyuki Tokunaga, Takashi Miyata, Yasuhiko Iida, Hiroatsu Nagai, Hirokazu Intern Med Case Report Acute promyelocytic leukemia (APL) in human immunodeficiency virus (HIV)-infected individuals is very rare. There is currently no consensus regarding the use of anti-cancer drugs with highly active anti-retroviral therapy (ART) in these patients due to their small number. We herein report two cases of APL with HIV-infected patients. Both cases received all-trans-retinoic acid-containing chemotherapies and achieved complete remission. ART was continued throughout the treatment course. The clinical course of these cases suggests that it is preferable to perform standard chemotherapy for APL with ART if patients have an adequate performance status. The Japanese Society of Internal Medicine 2019-05-22 2019-08-15 /pmc/articles/PMC6746639/ /pubmed/31118366 http://dx.doi.org/10.2169/internalmedicine.1662-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kunitomi, Akane
Hasegawa, Yuta
lmamura, Junji
Yokomaku, Yoshiyuki
Tokunaga, Takashi
Miyata, Yasuhiko
Iida, Hiroatsu
Nagai, Hirokazu
Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature
title Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature
title_full Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature
title_fullStr Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature
title_full_unstemmed Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature
title_short Acute Promyelocytic Leukemia and HIV: Case Reports and a Review of the Literature
title_sort acute promyelocytic leukemia and hiv: case reports and a review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746639/
https://www.ncbi.nlm.nih.gov/pubmed/31118366
http://dx.doi.org/10.2169/internalmedicine.1662-18
work_keys_str_mv AT kunitomiakane acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature
AT hasegawayuta acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature
AT lmamurajunji acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature
AT yokomakuyoshiyuki acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature
AT tokunagatakashi acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature
AT miyatayasuhiko acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature
AT iidahiroatsu acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature
AT nagaihirokazu acutepromyelocyticleukemiaandhivcasereportsandareviewoftheliterature

Ejemplares similares