CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis

Human mutations in carnitine palmitoyl transferase 1A (CPT1A) are correlated with a remarkably low prevalence of multiple sclerosis (MS) in Inuits (P479L) and Hutterites (G710E). To elucidate the role of CPT1A, we established a Cpt1a P479L mouse strain and evaluated its sensitivity to experimental a...

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Detalles Bibliográficos
Autores principales: Mørkholt, Anne Skøttrup, Trabjerg, Michael Sloth, Oklinski, Michal Krystian Egelund, Bolther, Luise, Kroese, Lona John, Pritchard, Colin Eliot Jason, Huijbers, Ivo Johan, Nieland, John Dirk Vestergaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746708/
https://www.ncbi.nlm.nih.gov/pubmed/31527712
http://dx.doi.org/10.1038/s41598-019-49868-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746708/
https://www.ncbi.nlm.nih.gov/pubmed/31527712
http://dx.doi.org/10.1038/s41598-019-49868-6

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