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HPV-positive status associated with inflamed immune microenvironment and improved response to anti-PD-1 therapy in head and neck squamous cell carcinoma
Chemotherapy and radiotherapy predominantly improve the clinical outcomes of patients with human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC). Whether this superiority goes on when treated with immune checkpoint inhibitors is still unclear. This study sought to determin...
Autores principales: | Wang, Jian, Sun, Hao, Zeng, Qin, Guo, Xue-Jun, Wang, Hui, Liu, Huan-Huan, Dong, Zhong-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746709/ https://www.ncbi.nlm.nih.gov/pubmed/31527697 http://dx.doi.org/10.1038/s41598-019-49771-0 |
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