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Touchscreen typing pattern analysis for remote detection of the depressive tendency

Depressive disorder (DD) is a mental illness affecting more than 300 million people worldwide, whereas social stigma and subtle, variant symptoms impede diagnosis. Psychomotor retardation is a common component of DD with a negative impact on motor function, usually reflected on patients’ routine act...

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Autores principales: Mastoras, Rafail-Evangelos, Iakovakis, Dimitrios, Hadjidimitriou, Stelios, Charisis, Vasileios, Kassie, Seada, Alsaadi, Taoufik, Khandoker, Ahsan, Hadjileontiadis, Leontios J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746713/
https://www.ncbi.nlm.nih.gov/pubmed/31527640
http://dx.doi.org/10.1038/s41598-019-50002-9
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author Mastoras, Rafail-Evangelos
Iakovakis, Dimitrios
Hadjidimitriou, Stelios
Charisis, Vasileios
Kassie, Seada
Alsaadi, Taoufik
Khandoker, Ahsan
Hadjileontiadis, Leontios J.
author_facet Mastoras, Rafail-Evangelos
Iakovakis, Dimitrios
Hadjidimitriou, Stelios
Charisis, Vasileios
Kassie, Seada
Alsaadi, Taoufik
Khandoker, Ahsan
Hadjileontiadis, Leontios J.
author_sort Mastoras, Rafail-Evangelos
collection PubMed
description Depressive disorder (DD) is a mental illness affecting more than 300 million people worldwide, whereas social stigma and subtle, variant symptoms impede diagnosis. Psychomotor retardation is a common component of DD with a negative impact on motor function, usually reflected on patients’ routine activities, including, nowadays, their interaction with mobile devices. Therefore, such interactions constitute an enticing source of information towards unsupervised screening for DD symptoms in daily life. In this vein, this paper proposes a machine learning-based method for discriminating between subjects with depressive tendency and healthy controls, as denoted by self-reported Patient Health Questionnaire-9 (PHQ-9) compound scores, based on typing patterns captured in-the-wild. The latter consisted of keystroke timing sequences and typing metadata, passively collected during natural typing on touchscreen smartphones by 11/14 subjects with/without depressive tendency. Statistical features were extracted and tested in univariate and multivariate classification pipelines to reach a decision on subjects’ status. The best-performing pipeline achieved an AUC = 0.89 (0.72–1.00; 95% Confidence Interval) and 0.82/0.86 sensitivity/specificity, with the outputted probabilities significantly correlating (>0.60) with the respective PHQ-9 scores. This work adds to the findings of previous research associating typing patterns with psycho-motor impairment and contributes to the development of an unobtrusive, high-frequency monitoring of depressive tendency in everyday living.
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spelling pubmed-67467132019-09-27 Touchscreen typing pattern analysis for remote detection of the depressive tendency Mastoras, Rafail-Evangelos Iakovakis, Dimitrios Hadjidimitriou, Stelios Charisis, Vasileios Kassie, Seada Alsaadi, Taoufik Khandoker, Ahsan Hadjileontiadis, Leontios J. Sci Rep Article Depressive disorder (DD) is a mental illness affecting more than 300 million people worldwide, whereas social stigma and subtle, variant symptoms impede diagnosis. Psychomotor retardation is a common component of DD with a negative impact on motor function, usually reflected on patients’ routine activities, including, nowadays, their interaction with mobile devices. Therefore, such interactions constitute an enticing source of information towards unsupervised screening for DD symptoms in daily life. In this vein, this paper proposes a machine learning-based method for discriminating between subjects with depressive tendency and healthy controls, as denoted by self-reported Patient Health Questionnaire-9 (PHQ-9) compound scores, based on typing patterns captured in-the-wild. The latter consisted of keystroke timing sequences and typing metadata, passively collected during natural typing on touchscreen smartphones by 11/14 subjects with/without depressive tendency. Statistical features were extracted and tested in univariate and multivariate classification pipelines to reach a decision on subjects’ status. The best-performing pipeline achieved an AUC = 0.89 (0.72–1.00; 95% Confidence Interval) and 0.82/0.86 sensitivity/specificity, with the outputted probabilities significantly correlating (>0.60) with the respective PHQ-9 scores. This work adds to the findings of previous research associating typing patterns with psycho-motor impairment and contributes to the development of an unobtrusive, high-frequency monitoring of depressive tendency in everyday living. Nature Publishing Group UK 2019-09-16 /pmc/articles/PMC6746713/ /pubmed/31527640 http://dx.doi.org/10.1038/s41598-019-50002-9 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Mastoras, Rafail-Evangelos
Iakovakis, Dimitrios
Hadjidimitriou, Stelios
Charisis, Vasileios
Kassie, Seada
Alsaadi, Taoufik
Khandoker, Ahsan
Hadjileontiadis, Leontios J.
Touchscreen typing pattern analysis for remote detection of the depressive tendency
title Touchscreen typing pattern analysis for remote detection of the depressive tendency
title_full Touchscreen typing pattern analysis for remote detection of the depressive tendency
title_fullStr Touchscreen typing pattern analysis for remote detection of the depressive tendency
title_full_unstemmed Touchscreen typing pattern analysis for remote detection of the depressive tendency
title_short Touchscreen typing pattern analysis for remote detection of the depressive tendency
title_sort touchscreen typing pattern analysis for remote detection of the depressive tendency
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746713/
https://www.ncbi.nlm.nih.gov/pubmed/31527640
http://dx.doi.org/10.1038/s41598-019-50002-9
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