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Identification of proteins and miRNAs that specifically bind an mRNA in vivo

Understanding regulation of an mRNA requires knowledge of its regulators. However, methods for reliable de-novo identification of proteins binding to a particular RNA are scarce and were thus far only successfully applied to abundant noncoding RNAs in cell culture. Here, we present vIPR, an RNA-prot...

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Detalles Bibliográficos
Autores principales: Theil, Kathrin, Imami, Koshi, Rajewsky, Nikolaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746756/
https://www.ncbi.nlm.nih.gov/pubmed/31527589
http://dx.doi.org/10.1038/s41467-019-12050-7