Metadherin enhances vulnerability of cancer cells to ferroptosis

Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death driven by lipid hydroperoxides within biological membranes. Although therapy-resistant mesenchymal-high cancers are particularly vulnerable to ferroptosis inducers, especially phospholipid glutathione peroxidase 4 (GPx4) in...

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Detalles Bibliográficos
Autores principales: Bi, Jianling, Yang, Shujie, Li, Long, Dai, Qun, Borcherding, Nicholas, Wagner, Brett A., Buettner, Garry R., Spitz, Douglas R., Leslie, Kimberly K., Zhang, Jun, Meng, Xiangbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746770/
https://www.ncbi.nlm.nih.gov/pubmed/31527591
http://dx.doi.org/10.1038/s41419-019-1897-2

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