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Design, synthesis, and discovery of novel oxindoles bearing 3-heterocycles as species-specific and combinatorial agents in eradicating Staphylococcus species

A series of new functionalized 3-indolylindolin-2-ones, 3-(1-methylpyrrol-2-yl)indolin-2-ones, and 3-(thiophen-2-yl)indolin-2-ones were synthesized by using novel indium (III)-catalysed reaction of various 3-diazoindolin-2-ones with indoles, 1-methylpyrrole, or thiophene via one-pot procedure. The n...

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Detalles Bibliográficos
Autores principales: Shin, Jonghoon, Magar, Krishna Bahadur Somai, Lee, Jungwoon, Kim, Kwang-sun, Lee, Yong Rok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746789/
https://www.ncbi.nlm.nih.gov/pubmed/31527598
http://dx.doi.org/10.1038/s41598-019-44304-1

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